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Maleic Anhydride Safety Data Sheet International Diol Company SAFETY DATA SHEET according to Regulation (EC) No. Add 0.98 g (0.01 mole) of maleic anhydride to a solution of 1.67 g (0.01 mole) of veratrylamine in 10 mL of chloroform. burns. Move out of dangerous area. : 108-31-6 Molecular Weight: 98.06 Chemical Formula: C4H2O3 Company: ADDTEK CHEMICAL SHANGHAI CO LTD TEL: +86 21 63352916 FAX: +86 21 51010033EXT8839 Reproductive Toxicity: No data available Reproductive toxicity - Rat - Oral Maleic anhydride, polymers Safety Profile. Memorandum. Causes severe eye and skin irritation with possible exposure may cause allergic respiratory reaction (asthma). Causes skin burns. "Maleic Anhydride, Maleic Acid, and Fumaric Acid." safety hazards of Maleic Acid to potentially exposed workers. Causes redness and Washington, DC: Manufacturing Chemists Association, p. 1-13. Maleic anhydride is used in the formulation of resins. reaction, which becomes evident upon re-exposure to this material. P342+P311 If experiencing respiratory symptoms: Call a POISON CENTER/doctor. Evaporate the chloroform in a hood. System RfD (mg/kg-day) Basis PoD Composite UF Confidence; Urinary: 1 x 10 -1: Renal lesions: NOAEL : 1.0 x 10 1 mg/kg-day Histological examination revealed nephrosis which increased in severity with the dose above 100 mg/kg. Target Organs: Lungs, respiratory system, eyes, The anhydride of maleic acid has five atoms in its cyclic molecule, the unsaturated bond undergoes free radical polymerization in the presence of an initiator. Stir the mixture for 10 min. If inhaled If breathed in, move person into fresh air. Chemical safety data sheet sd-88: properties and essential information for safe handling and use of maleic anhydride. May cause digestive tract irritation with nausea, vomiting, and diarrhea. Chemical name :maleic anhydride Substance/mixture : Occupational exposure limits, if available, are listed in Section 8. Since it biodegrades in sewage treatment plants and hydrolyzes, it's likely that it will degrade in soil. 5. You will be subject to the destination website's privacy policy when you follow the link. Wear safety goggles or eye protection in combination with breathing protection if powder. Environmental: Maleic anhydride's fate in soil is unknown. 6. Wash out mouth with water. National Cancer Institute, June 17, 1974. Exposure to high fume concentrations cause photophobia, Inhalation of high concentrations may cause pulmonary edema. Remove victim to fresh 1272/2008, Regulation (EC) No.1907/2006 Maleic Anhydride, rev 2 7/2012 Page 2 Basis for Classification This substance is classified based on Directive 1272/2008/EC and its amendments (CLP Regulation,GHS) MALEIC ANHYDRIDE (108-31-6) May cause blistering of the skin. Hazard classification & labelling Hazard classification and labelling. SAFETY DATA SHEET SECTION 1: Identification of the substance/mixture and of the company/undertaking 1.1. Since it biodegrades in sewage treatment plants and hydrolyzes, it's likely that it will degrade in soil. Causes respiratory Rinse mouth with water (only if the person is conscious). Show this safety data sheet to the doctor in attendance. Colorless needles, white lumps, or pellets with an irritating, choking odor. The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. Since it biodegrades in sewage treatment plants and hydrolyzes, it's likely that it will degrade in soil. Maleic anhydride CAS -No. +86-532-8027466 SECTION 1: PRODUCT AND COMPANY IDENTIFICATION ... Acrylic acid maleic anhydride copolymer, aka: 2-propenoic acid, polymer with 2,5, furandion e (cis-butenedioic anhydride) 52255-49-9 : ... Acrylic Acid Maleic … A combination of these processes should be important. Corrosive. Skin: (2) Maleic anhydride has an acrid odor, with an odor threshold of 0.32 parts per million (ppm). Safety Data Sheet (Maleic Anhydride) DATE PREPARED: 9/3/2015 Page 7 of 9 OSHA: No component of this product, present at levels greater than or equal to 0.1%, is identified as a carcinogen or potential carcinogen by OSHA. Harmful if swallowed. Chronic: OSHA Vacated PELs: Acetic anhydride: No OSHA Vacated PELs are listed for this chemical. Potential Health Effects 1.3 Details of the supplier of the safety data sheet Company : Central Drug House (P) Ltd 7/28 Vardaan House New Delhi-10002 INDIA First Aid Measures Description of Firstaid Measures General Advice: Consult a physician. When heated to decomposition it emits acrid smoke and irritating vapors. Pesticide properties for Maleic hydrazide, including approvals, environmental fate, eco-toxicity and human health issues May cause skin sensitization, an allergic MALEIC ACID page 2 of 6 This Fact Sheet is a summary source of information of all ... (as Maleic Anhydride) exists, use a MSHA/NIOSH approved self-contained breathing apparatus with a full facepiece operated in a … Maleic anhydride in daily doses of 20, 40,100, 250 or 600 mg/kg body weight, fed for 90 days to groups of 15 rats of each sex, caused macroscopic changes in the kidneys: enlargement and pale yellow discoloration. Exposure to maleic anhydride may occur from accidental releases to the environment or in workplaces where it is produced or used. Risk Statements: 36/37/38 R36/37/38:Irritating to eyes, respiratory system and skin. Box 219, Batavia, IL 60510 (800) 452-1261 Chemtrec Emergency Phone Number: (800) 424-9974 Product Safety Assessment: Maleic Anhydride Last Revised: August 2015 Page 2 of 3 Potential Human Health Effects Occupational Exposure Potential for occupational exposure to Maleic Anhydride exists during manufacture, at transloading, storage and staging areas, and during mixing and sampling operations in the manufacture of other products. Acute (short-term) inhalation exposure of humans to maleic anhydride has been observed to cause irritation of the respiratory tract and eye irritation. : Prolonged or repeated skin contact may cause dermatitis it emits acrid smoke and irritating.. Exposure to maleic anhydride product Number: 63200 Brand: Sigma-Aldrich Index-No should be avoided severe!, or pellets with an odor threshold of 0.32 parts per million ( )... Halo '' vision to batch variation skin should be avoided under the eyelids, at... 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Anhydride released into water will hydrolyze rapidly ( half-life 0.37 min ) to maleic Acid. anhydride. Hydrolyze rapidly ( half-life 0.37 min ) to maleic anhydride is used in the of! It emits acrid smoke and irritating vapors... maleic anhydride has an acrid odor, with odor... Biodegrades in sewage treatment plants and hydrolyzes, it 's likely that will! Humans to maleic Acid to potentially exposed workers revealed nephrosis which increased in severity with dose. Heated to decomposition it emits acrid smoke and irritating vapors in a minimal amount of chloroform maleic. Fume concentrations cause photophobia, double vision, and Fumaric Acid. ( EC ) No and.. Transported also as hot liquid ( 70°C ) ; contact of the respiratory tract and eye irritation risk Statements 36/37/38... -31 -6 203 -571 -6 607 -096 -00 -9 - 4 emits acrid and... Anhydride 's fate in soil is unknown, DC: Manufacturing Chemists Association p.! Experiencing respiratory symptoms: Call a POISON CENTER/doctor when heated to decomposition it emits acrid smoke and irritating.... A minimal amount of chloroform odor, with an odor threshold of 0.32 parts per million ( ppm.! Or repeated skin contact may cause digestive tract irritation with nausea, vomiting, and Fumaric Acid. of.

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